Brian O. Bachmann (Curriculum Vitae) is Associate Professor at the Vanderbilt University Department of Chemistry. He earned his B.S. in Chemistry from Virginia Tech, M.S. from Southern Methodist University, and Ph.D from the Johns Hopkins University.
Prior to arriving at Vanderbilt University, Professor Bachmann was Director of Chemistry at Ecopia Biosciences, a natural product-based drug discovery company in Montreal, Quebec. Professor Bachmann has served as a scientific consultant for multiple corporations, and as a Board of Directors member. He holds several U.S. and international publications and patents.
Professor Bachmann is Principal Investigator of the Laboratory for Biosynthetic Studies, a multidisciplinary group working on the construction and deconstruction of biosynthetic pathways. The broad goals of this group are to investigate how natural product biosynthetic enzymes evolve and to understand the design rules for their concatenation into efficient “total syntheses” of natural products. Can we apply these rules and direct the evolution of these pathways into new biosynthetic pathways of our own design?
The impacts of this work include providing new avenues for drug discovery by combinatorial biosynthesis and “green” cost-effective ways of producing high-value products and intermediates for pharmaceutical and life sciences.