Fluorescent probes of the apoptolidins and their utility in cellular localization studies uses actinomycete engineering to help generate probes to study MOA of apoptolidin.
Pharmacology and Chemical Probe Development of the K-26 Family of Natural Product Angiotensin-! Converting Enzyme Inhibitors. Congrats
In collaboration with the Iverson group, we demonstrate the first application of the retro-evolution hypothesis.